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S-Adenosyl-L-Methionine (SAMe) is a natural compound and methyl group donor that supports the methylation cycle, a process which is essential for many aspects of health.


SAMe’s effectiveness to support a balanced mood is demonstrated by many clinical studies. SAMe has also been found to support joint health in osteoarthritis patients as effectively as a popular anti-inflammatory drug by reducing inflammation and protecting joint tissue from degradation.


AOR Advantage

AOR introduced the first SAMe supplement to Canada in 2000.  AOR’s SAMe 400™ provides a clinically researched dose in an enteric-coated tablet for convenience.

AOR - SAMe 400

  • Supports a balanced mood

    • Boosts mood and emotional well-being
    • Relieves symptoms of osteoarthritis
    • Provides a researched dose in a convenient form of SAMe
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